Mole, an anthropomorphised mole, a main character in the children's novel Wind in the Willows by Kenneth Grahame

The Mole, a reality television series

Mole plough, a deep plough for cutting buried drainage channels under wet farmland

Adrian Mole, a fictional diarist in a series of novels by Sue Townsend

River Mole, Surrey, a river, part of whose course runs underground in dry weather

Mole (unit), the SI unit (symbol mol) used in chemistry for the amount of a particular substance

Mole salamander, a burrowing salamander in the family Ambystomatidae

Hydatidiform mole, a medical condition

Mole, a tunnel boring machine

Golden mole, a burrowing insectivorous mammal in the family Chrysochloridae, not closely related to true moles

Mole (animal) or mouldywarp, a burrowing insectivorous mammal in the family Talpidae, with short velvety fur and enlarged front limbs. The origin of a number of other meanings:

Marsupial mole, a mole-like marsupial

Mole (sauce), a Mexican sauce made from chilli peppers and other spices, including chocolate

Mole wrench, a generic term in the UK for vice-grips or lock-jaw pliers, named after a trade name for such tools

Mole, a melanocytic nevus, a small area of skin, sometimes raised, with darker pigment

The Mole (emcee/producer), underground hip hop personality

Moleskin, originally the skin of a mole, but later a heavy, soft, durable cotton fabric, or clothing made from this

Type 33 Mole aircraft, the Beriev Be-8

Mole Antonelliana, a major landmark in Turin

Mole (espionage), a spy buried secretly within an organisation or country

Mole (Zdeněk Miler character), an animated character

Mole cricket, a mole-like cricket in the family Gryllotalpidae

Molehill (or mole-hill), a conical pile of soil pushed up at intervals by moles or other burrowing animals when digging burrows, especially beneath grassland or lawns

Mole (architecture), a massive structure, usually of stone, used as a pier, jetty, breakwater, or junction between places separated by water

Mole-rats, rodents of several different families which live underground like moles