Medininkai can refer to several things in Lithuania:

Medininkai Land, a medieval administrative unit in the Grand Duchy of Lithuania. The capital was Varniai, then known as Medininkai

Medininkai Reserve, a reserve established in 1974 to protect arnica montana and other rare plants

Medininkai glaciation, a glaciaton in the Middle Pleistocene period

Medininkai Gate, an alternative name for Gate of Dawn in Vilnius

Varniai, city in Lithuania, was previously referred to as Medininkai

Medininkai Castle, a castle in the village

Medininkai, a village in Lithuania

Medininkai Incident, when Soviet OMON killed seven and critically wounded one Lithuanian boarder guards