Colleen McCullough (born 1937), Australian author

Bernie Mac (born 1957), comic-actor born Bernard McCullough

McCollough effect, a phenomenon of human visual perception

Kimberly McCullough (born 1978), American actress

David McCullough (born 1933), American historian and author

Wayne McCullough (born 1970), professional boxer

Julie McCullough (born 1965), American model and actress

Conde McCullough (1887-1946), U.S. bridge engineer

Henry McCullough (born 1943), musician

Warren Sturgis McCulloch (1899–1969), neurophysiologist and cybernetician

J.J. McCullough, Canadian cartoonist

Denis McCullough (1883–1968), Irish rebel in the early 20th century.

Billy McCullough (born 1935), former Northern Ireland footballer

Jimmy McCullough (1953–1979), Scottish musician

Douglas McCullough, American judge

John Edward McCullough (1837-1885), American actor

Hiram McCullough (1813-1885), U.S. Congressman from Maryland

Helen Craig McCullough (1918-1998), scholar of classical Japanese poetry and prose

Shanna McCullough (born 1960), adult film star

J. McCullough a Scottish author and avid golfer of the late 19th century

Sultan McCullough (born 1980), National Football League running back

Clyde McCullough (1917-1982), Irish baseball player

Suli McCullough (born 1968), comic-actor and writer

John C. McCullough (1858-1920), former Attorney General of California