Matrix (mathematics), a mathematical table

Autobot Matrix of Leadership, a talisman in the fictional Transformers Universe

Matrix (fictional universe), the world referred to in the Matrix series

John Matrix, Arnold Schwarzenegger's character in Commando (film)

Growth-share matrix, a Boston Consulting Group analysis technique for business strategy

Extracellular matrix, any material part of a tissue that is not part of any cell

Substitution matrix, which estimates the rate at which each possible residue in a biological sequence changes to each other residue over time

Metal matrix composite, a type of composite material

Toyota Matrix, an automobile produced by Toyota

Matrix (Doctor Who), an advanced computer network and a virtual reality environment from the British television series Doctor Who

Matrix management, an organizational management style

Matrix isolation, a continuous solid phase in which particles (precipitates, etc.) are embedded

Position-specific scoring matrix, which represents a pattern or motif in biological sequences

Matrix (geology), the fine grains between larger grains in igneous or sedimentary rocks

Osteon or bone matrix, a form of connective tissue found in bone

Similarity matrix, which scores the similarity between two data points

The Matrix (music producer), a music production team

Nuclear matrix, an insoluble fraction of the cell nucleus

The 1997 remix album by the German band Haujobb

Hyundai Matrix, an automobile produced by Hyundai

Matrix (music), an element of variations which does not change, especially in folk and popular music

Matrix (sound recording), a disc in the early stages of processing a record for mass production

Matrix (biology), the material between animal or plant cells or the material in the inner membrane of a mitochondrion

Matrix (TV series), an early 1990s Canadian television series

The Matrix (club), a 1960s music club in San Francisco

Matrix (printing), a mold for shaping the letters

Matrix (artist), a UK drum and bass producer

Matrix (club), a large music club which opened in 1996 in Berlin

Matrix (Doctor Who novel), a Doctor Who novel by Robert Perry and Mike Tucker

Matrix Software License Protection System, a product from TDi GmbH, Germany

Alfa Matrix, a record label

Matrix (numismatics), an intermediate into which the design of a coin is engraved

Matrix (jazz group), a jazz fusion ensemble founded in the 1970s

Germinal matrix, an embryonic brain tissue

M@rix (pronounced Matrix) the 1997 album by the German band P.A.L.

Nickname of Italian footballer Marco Materazzi