Manuel I Komnenos (1118–1180), Byzantine emperor

Manuel II Palaiologos (1350–1425), Byzantine emperor

Manuel I of Portugal (1469-1521)

Manuel II of Portugal (1889-1932)

Manuel, Prince of Portugal (1531-1537), son of John III of Portugal

Infante Manuel, Count of Ourém, Portuguese prince, son of Peter II of Portugal

Manuel III of Trebizond (1364–1417)

Manuel (Fawlty Towers), waiter in the BBC TV sitcom

Manuel I of Trebizond (1218–1263)

Manuel II of Trebizond (1324–1333)

Stage name of Geoff Love (1917-1991), British easy-listening orchestra leader

Manuel, Lord of Villena (1234-1283), son of Ferdinand III of Castile

Manuel, Valencia, a municipality in the province of Valencia, Spain

Manuel (name)

Manny Ramirez, baseball player, currently playing for the Boston Red Sox