Mystery Science Theater 3000, an American cult television comedy series

A Mesosphere-Stratosphere-Troposphere radar

Mean Square for Treatments, in analysis of variance

"Mystical Space Typhoon", a card in the Yu-Gi-Oh! trading card game

Madison Symmetric Torus, a physics device at the University of Wisconsin-Madison, U.S.

Missouri University of Science and Technology, in Rolla, Missouri

Multiple Spanning Tree protocol or Spanning tree protocol, for networks

Landless Workers' Movement or in Portuguese, Movimento dos Trabalhadores Rurais Sem Terra (MST), in Brazil

Minimum spanning tree, in graph theory

Monterey-Salinas Transit, provides bus service within Monterey County in California

Malaysian Standard Time, UTC + 8hr

Math/Science/Technology program at the Utica Center for Math, Science, and Technology

MicroSystems Technology / MicroStructure Technology, the technology of the very small, MEMS, Micromachines

Math Science Technology (MST) program at Chaminade College School, Toronto, Ontario, Canada

Mountain Time Zone, Mountain Standard Time UTC -7hr in North America

Socialist Workers Movement (Puerto Rico) or Movimiento Socialista de Trabajadores in Puerto Rico

Maastricht Aachen Airport, the IATA code for the airport in the Netherlands

Manchester School of Technology, in Manchester, New Hampshire

Evolutionary metasystem transition theory

Master of Science in Taxation, a professional graduate degree

Medial superior temporal area, an area of the neocortex (of the primate brain)