LOCI or LO:CI, a fan shorthand for the TV series Law & Order: Criminal Intent

LOCUS Operating System started as a clustering OS research project at UCLA, and was then developed into a commercial product by Locus Computing Corporation in the 1980s

Loci is a nickname for rapper Ja Rule

Locus (law), in Scots Law, the place which is the location of a crime or incident subject of lawful or legal enquiry

Locus (psychology), in industrial psychology, having an internal or external locus of control

The word locus (plural loci) is Latin for "place":

Locus, is a racing computer game set in the future

method of loci, a mnemonic system

Locus (mathematics), the set of points satisfying a particular condition, often forming a curve of some sort

Locus (comics), a Marvel Comics Mutant and supervillain

Locus (genetics), the position of a gene (or other significant sequence) on a chromosome

Locus Computing Corporation developed the LOCUS clustering operating system, as well as the Merge 8086 virtual machine implementation.

Locus Plethore, a Canadian supercar

Locus (magazine), a magazine carrying news about science fiction

Locus Award, presented to the winners of Locus magazine's annual readers' poll

LOCUS (Level of Care Utilization System), a clinical level of care placement tool for psychiatric and addictions services, developed by the American Association of Community Psychiatrists

Locus Suspectus, a Canadian contemporary arts magazine

Locus (phonetics), the hypothetical starting point of the formant transitions that characterise plosive consonants acoustically

In the classics, literature or theology, locus (or locus classicus) marks the first appearance of a phrase or the definitive passage that is authoritative for an idea