Fiorello Henry LaGuardia, (1882 - 1947), the Republican Mayor of New York from 1934 to 1945. He was popularly known as "the Little Flower," the translation of his Italian first name, also perhaps a reference to his short stature of just 5 feet.

Little Flower (小花 -Xiao Hua), a 1979 movie starring Joan Chen for which she was awarded the Hundred Flowers Award for China's Best Actress.

Basilica of the National Shrine of the Little Flower in San Antonio, Texas

National Shrine of the Little Flower in Royal Oak, Michigan

Thérèse de Lisieux, (1873 - 1897), a nun who was declared by the Roman Catholic Church as a Saint and a Doctor of the Church. She is widely known as "The Little Flower of Jesus".