le, a word derived from the Latin ille and used in French, Spanish and Italian, as a definite article and a pronoun.

The NATO country code for Lebanon

Left Eye, an abbreviation used sometimes in optometry.

Life Extension, increasing human lifespan by slowing or reversing the processes of aging

Lupus erythematosus, an autoimmune disease

The British post code for the Leicester region in the East Midlands

Local Exchange, see Telephone exchange

Less than or Equal to, sometimes written as <math>\le</math> or "<=", see Inequality

Low Evaporation, an attribute of some liquids

Little Endian, see Endianness

"Language Environment", an IBM mainframe feature

Egyptian pound, LE stands for livre égyptienne (French for Egyptian pound)

Long exposure (photography)

Leading edge, the forward-most edge of a wing

Luxury edition (cars)

Lewis number, in physics

Lê, a common Vietnamese surname

Law enforcement (also LEO for Law Enforcement Officer, or for Wikiproject Law Enforcement)

Lawful Evil, an Alignment in the Dungeons & Dragons role-playing game

Long Éireannach (Irish Ship), a ship prefix for Irish vessels (abbreviated to LÉ)