"The Killers" (short story), a 1927 short story by Ernest Hemingway.

The Killers (1946 film), a film adaptation of the story starring Burt Lancaster and Ava Gardner.

The Killers (band), a rock band from Las Vegas, Nevada.

Killers, a band led by Paul Di'Anno from 1991 to present, named after his most popular Iron Maiden album; sometimes called "Paul Di'Anno's Killers" or "Paul Di'Anno and the Killers".

Killers (Iron Maiden album), the second album from British heavy metal band Iron Maiden.

Killers (Kiss album), the 1982 greatest hits album from the American glam rock band Kiss.

Live Killers, a 1979 live album by Queen.

The Killers (1964 film), a film adaptation of the story starring Ronald Reagan, Angie Dickinson and Lee Marvin.

The Killers (1956 film), a film adaptation of the story directed by Andrei Tarkovsky.

"Killers", a song by Pantera from their 1984 album Projects in the Jungle.

Killers (film), a 2003 compilation of five short films by Japanese directors.

"Killers" (song), the title song of the above album

The Killers (1984 film), a film starring Jack Kehoe.