Ie (novel), a work of Japanese author Shimazaki Toson

Inland Empire (California), in the United States

Internet Explorer, the web browser by Microsoft

International English, the concept of the English language as a global means of communication

Indo-European languages

Industrial engineering, the engineering discipline that concerns the development, improvement, implementation and evaluation of integrated systems of people, knowledge, equipment, energy, material and process

Indo-European studies

Industrial Ecology, the study of sustainable industrial systems.

Iced Earth, a power metal band from the United States

Information engineering, an approach to designing and developing information systems

Iarnród Éireann, or Irish Rail

A spelling guideline of the English language: "i before e except after c"

Ionization energy, the energy required to strip an atom or molecule of an electron; see Ionization potential.

Solomon Airlines, IATA airline designator

Information extraction, a type of information retrieval whose goal is to automatically extract structured or semistructured information from unstructured machine-readable documents

Ie (trading houses), Japanese cottage industry

The ie (digraph)

Infinity Engine, the game engine behind Baldur's Gate among others.

Indo-European (disambiguation), as in:

Indo-European people

Institute for Energy of the European Union

Ie (Japanese family system), the classical Japanese family system

Information Element, a networks abbreviation

Ie, the West Frisian name of the Dutch village of Ee, Dongeradeel.

Ie, Okinawa, in Japan

-ie, an English diminutive suffix

.ie in ISO standards:

Interlingue, originally the Occidental language (ISO 639-1)

Republic of Ireland (ISO 3166-1 alpha-2)