International Monetary Fund, the international organization that oversees the global financial system

Intermolecular Force, bonds that bind chemical compounds together.

Intramuscular fat, in cuts of meat.

Internationale Medien und Film, see Intermedia (production company)

International Music Feed, a music video television network

Initial mass function, in stellar astronomy

Interplanetary Magnetic Field, in Space Physics

IMF (music), music file format used in video games

International Metalworkers' Federation, a global union federation

Inframammary fold

Impossible Missions Force, a fictional secret espionage agency in the Mission: Impossible television series and series of movies

Inert Matrix Fuel, a nuclear fuel form employing non-fertile material to efficiently reduce Plutonium stockpiles in a peaceful fashion