Hypatia of Alexandria (?370–415), a neo-Platonic philosopher, mathematician, and teacher.

Hypatia (crater), a lunar crater that lies along the northwest edge of Sinus Asperitatis, a bay on the southwest edge of Mare Tranquillitatis.

238 Hypatia, a very large Main belt asteroid. It is classified as a C-type asteroid and is probably composed of primitive carbonates.

This same Hypatia is a historical figure in the alternate history/fantasy series The Heirs of Alexandria by Mercedes Lackey, Eric Flint and Dave Freer.

This same Hypatia is a character in the novel "Baudolino" by Umberto Eco.

Hypatia: A Journal of Feminist Philosophy, scholarly publication for research in feminism and philosophy.

Hypatia (novel), written in 1853 by Charles Kingsley.