Alger Hiss, a U.S. State Department employee and alleged spy for the Soviet Union

King Hiss, the villainous king of the Snake Men in Mattel toyline Masters of the Universe

Electronic circuit hiss, white noise present at low level in all electronic circuits

Sir Hiss, Prince John's fictional sidekick in the 1973 animated Disney movie Robin Hood

Donald Hiss, younger brother of Alger Hiss

Mike Hiss, a former driver in the USAC Championship Car series

Tape hiss, high frequency noise present on analogue magnetic tape recordings

An onomatopoeia for a type of noise comparable to white noise, such as the release of air brakes. The noise is characteristic of some snakes and also commonly produced by cats and people with a lisp.