Sun, a star

Helios, a "persona" in the Playstation games Persona 2: Innocent Sin and Eternal Punishment

Helios Airways Flight 522, a Helios Airways Boeing 737-31S flight that crashed on August 14, 2005 into a mountain north of Marathon and Varnavas, Greece

Helios, a wrestler for Chikara (professional wrestling)

Helio (wireless carrier), U.S. wireless carrier, launched May 2006, joint venture between SK Telecom (South Korea) and Earthlink

Helios (lens brand), a brand of lens, made in the USSR, supplied with Zenit cameras, often usable with other M42 lens mount cameras

HeliOS, a Unix-like operating system

Helio Courier, a light C/STOL utility aircraft designed in 1949

Helios Airways, former low-cost airline operating scheduled and charter flights between Cyprus and many European destinations

Helios Prototype, a series of solar- and fuel cell system-powered unmanned aircraft

Heliotropism, the diurnal motion of plant parts (flowers or leaves) in response to the direction of the sun

FC Helios Kharkiv, a football(soccer) team from Ukraine

Helios probes, deep space probes were launched in the mid 1970s by the Federal Republic of Germany and NASA

The Helio Sequence, an indie electronica/shoegazer band

895 Helio, a minor planet orbiting the Sun

Helios (cinemas), a multiplex cinema operator in Poland

Helios (artist), moniker of the instrumental ambient artist Keith Kenniff

Helios (propulsion system), a nuclear pulse propulsion system invented by Freeman Dyson, a precursor to his Project Orion

Helio (comics), a fictional character in the Marvel Universe

Helio Alves (born São Paulo, 1966), jazz pianist and son of pianists

KK Helios Domžale, a basketball club from Slovenia.

Helios 1B and Helios 2A, French military satellites

Helios, an AI in the computer game Deus Ex, the sum of the merged Daedalus and Icarus AIs

Hélio Castroneves, Brazilian race car driver in the IRL series

Hélio Gracie, Co-founder of Brazilian Jiu-Jitsu