Heart of Darkness is a novella by Joseph Conrad. Its story was later adapted to become the basis for the film Apocalypse Now.

The Heart of Darkness is the source of Kain's vampiric life, and an important plot element in the Legacy of Kain video game series.

Hearts of Darkness: A Filmmaker's Apocalypse, a documentary about the making of the film Apocalypse Now.

Heart of Darkness (album), an album by the band Grave Digger.

Heart of Darkness (game), a video game, a relative of Another World.

Heart of Darkness (song), a song by death metal band Arch Enemy on their album Wages of Sin.

The Heart of Darkness, the debut album by the band Hoodlum Priest.