Handy Andy (film), a 1934 film starring Will Rogers

Handy Andy (household cleaner), a widely-recognized brand of cleaning product in South Africa

Handy Andy (toy character), a toy character produced by Student Unions & Activities at the University of Minnesota related to the Handy Andy's Key Quest video game.

Handy Andy Home Improvement Center, a defunct big box hardware store

Handy Andy (comic strip), a strip in the British comic Krazy

Handy Andy (tools), a brand of children's carpentry tools

Andy Kane, a carpenter in the influential BBC DIY TV show Changing Rooms