The abbreviation HSR may stand for:

High speed rail generally

The Taiwan High Speed Rail specifically

Hungarian Soviet Republic

Hamilton Street Railway

Horseshoe Scout Reservation

Hart-Scott-Rodino Antitrust Improvements Act

Henson Scout Reservation, a Boy Scout Reservation on the Eastern Shore of Maryland.

Health Services Research

Homogeneously staining region

Hierarchical state routing is a routing protocol for Ad hoc networks

Historic Sportscar Racing, a historic auto racing series in the USA