Hampden-Sydney College

Hematopoietic stem cell

Home Shopping Club, the old name of the Home Shopping Network

Higher School Certificate (New South Wales, Australia)

Hindu students council

Hospital for Sick Children (Toronto, Canada)

Hydraulic Sinus Condensing, a technique used in dentistry to lift the sinus

Houston Ship Channel

Hughes Systique Corporation

Harmonized System Code

Heraldry Society of Canada

High Speed Craft

Center for Studying Health System Change

HyperShape/CATIA, a software developed by Altair Engineering

Higher Secondary (School) Certificate (Bangladesh & India)

Hitachi Storage Cluster

HSC50 (Hierarchical Storage Controller Model 50), a mass storage controller from Digital Equipment Corporation implementing their Mass Storage Control Protocol

The NYSE ticker symbol for Harsco Corporation