Great Northern bean, a white common bean.

Great Northern War, a war fought by Russia, Denmark-Norway, and Saxony-Poland against Sweden

Main North railway line, New South Wales (Australia), also known as the Great Northern Railway.

Great Northern Railway (Great Britain)

Great Northern Railway (U.S.)

Great Northern Railway (Ireland)

The Great Northern Warehouse, a leisure complex in Manchester, England.

Great Northern Diver (Gavia immer), a bird also known as the Common Loon

Great Northern (band), an indie pop group from the USA

Great Northern?, a novel by Arthur Ransome in the Swallows and Amazons series, named after the diver.

Great Northern route, a group of railway services north of London, UK

Great Northern (starship), a fictional starship appearing in a number of Stephen Baxter's novels