Electro-chemical impedance spectroscopy, see spectroscopy

Epigenetic inheritance system, a concept in genetics

Environmental impact statement, an assessment of the likely impact a project may have, required for projects receiving federal funding in the United States

Electrical insulation system, see electrical insulation

Executive Information System, a form of decision support system

Escuela Internacional Sampedrana, a school in Honduras

Eastern Independent Schools of Melbourne, a group of schools in Australia

Enhanced Imaging System, a US satellite project

Enterprise Investment Scheme, a UK tax term

Esquadron d'Intervention Spécial, the former name of the Belgian police's counter-terrorism unit

Enterprise Information System, an organization-wide information system

English Institute of Sport, a network of sports related services

Epidemic Intelligence Service, a US training program

Educational Institute of Scotland, a Scottish teachers' trade union

Electrolyte-Insulator-Semiconductor, a sensor

European Integration Studio, an Electronic Arts studio

Electronic Instrument System, a component of the Glass cockpit in an MD-11 Aircraft

Terrance B. Lettsome International Airport, an airport in the British Virgin Islands which has IATA airport code EIS