Dave, Shelly, and Chainsaw, a morning radio program in San Diego, California, United States

Doctor of Surgical Chiropody is a degree superseded in 1960's by Doctor of Podiatric Medicine

Digital still camera

Distinguished Service Cross (United States) — an American military award.

Discovery Channel Pro Cycling Team - DSC is the team's UCI code

Dynamic stability control — also known as Electronic Stability Program in automotive engineering

Dye-sensitized solar cell

Digital Selective Calling is a component of the Global Maritime Distress Safety System

Differential scanning calorimetry, or the differential scanning calorimeter

D.Sc. — a Doctor of Science

Dresdner Sport Club, a German football club.

Digital Enhanced Cordless Telecommunications — an Encryption algorthim used by DECT wireless telephone handset

Document Structuring Conventions in PostScript programming

Dixie State College of Utah

Dirty South County - a hip hop group from Dallas, Texas

Distinguished Service Cross (UK) — a British naval award.

Daily Source Code, a podcast by Adam Curry

Digital Signal Controller, A hybrid microcontroller and digital signal processor

Distinguished Service Cross (Australia) is an Australian military award

DSC is an initialism or abbreviation for:

The Divide Social Club, a worldwide social group created by Heroes star Milo Ventimiglia and his 2 friends Dino DeMilio and Russ Cundiff. Membership is for life.