Channel (marketing), the distribution "channel" for selling and delivering a product or service to a company's customers

English channel, the part of the Atlantic Ocean that separates Great Britain from northern France

Wii Menu, the channels-operated interface for the Wii console

Canal, a manmade water channel

Ion channel, a channel in a plasma membrane which helps certain ions to enter/exit a biological cell

Medium (spirituality), through which disembodied spirits speak

Channel (Chinese medicine), also known as "Meridian", common name of vessel and collaterals

Channeler (The Wheel of Time), people who can wield the One Power in the fantasy series by Robert Jordan

Channel (communications), the route which a message follows

Chanel, a Parisian fashion house

Channel (geography), the course traveled by a body of water: (a) between land masses or (b) as a river or slough

Channel (digital image), the black and white representation of a specific color

Television channel, a television station or its cable/satellite counterpart

Channel Home Centers, a now-defunct home improvement chain (similar to Home Depot) based in the northeast USA.

Scattering channel, in scattering theory, a possible state of the colliding system

Active Channel, a website type which was introduced by Internet Explorer 4.0 in 1997

Channel (football), football (soccer) terminology for particular areas of the pitch.

Stereophonic sound, 2 channel stereo; Quadraphonic sound, 4 channel stereo

Channels (band), a rock band fronted by ex-Jawbox singer/guitarist J. Robbins