Tropic of Cancer, a major circle of latitude

Cancer, the group of malignant diseases

Cancer on the Presidency, a recorded conversation between U.S. President Richard M. Nixon, his lawyer John Dean, and White House Chief of Staff H.R. Haldeman discussing the Watergate scandal

Cancer (constellation), the constellation

Cancer (astrology), the astrological sign

Cancer (genus), a genus of crab

Cancer (band), a British death metal band

Cancer (comics), a Marvel Comics character

"Cancer", a song by Joe Jackson on his 1982 album Night and Day.

"Cancer", a song by Filter on their 1999 album Title of Record.

"Cancer", a song by My Chemical Romance on their 2006 album The Black Parade.

55 Cancri, a star system 40 light years away from Earth in which NASA has recently discovered five planets