Calpurnia, the cook and maid to the Finch family in To Kill a Mockingbird.

Calpurnia, third and last wife of Pliny the Younger and granddaughter of Arrius Piso

2542 Calpurnia, an asteroid discovered by E. Bowell on 11 February 1980

Calpernia Addams, an American transgender author and activist

Calpurnia Pisonis, third and last wife of Julius Caesar

Calpurnia (genus), a genus in the family Fabaceae composing of shrubs and other small trees, usually found in southern Africa

Gens Calpurnia, a noble family

Lex Calpurnia (149 BC), a law that established a permanent extortion court

Lex Acilia Calpurnia (67 BC), a severe law against political corruption