Cairo Trilogy, a trilogy of novels written by Naguib Mahfouz

Cairo (1942 film), an American film starring Jeanette MacDonald

Cairo is the capital city of Egypt. It may also refer to:

Cairo Station, a fictional orbital Super MAC defence platform in the Halo 2 video game

Cairo, Illinois

Cairo (1963 film), an American film starring George Sanders

Cairo Apartment Building in Washington, D.C.

Cairo Gang, a group of 18 MI5 agents sent to Dublin during the Anglo-Irish War

USS Cairo (1861), an ironclad river gunboat in the United States Navy during the 19th century

Cairo, Ohio

Cairo, Georgia

Cairo Township, Minnesota

Pieve del Cairo, a comune in the Italian region Lombardy

Cairo (town), New York

cairo (graphics), the free software vector graphics library

Cairo (operating system), the internal Microsoft code name for a 1990s technology project

Cairo Montenotte, a comune in the Italian region Liguria

Cairo, Missouri

Cairo, West Virginia

Miguel Cairo, a Major League Baseball player

L'oca del Cairo, an opera buffa

Cairo poets, a literary group based in Cairo, Egypt during World War II

Cairo 52, a term referring to an incident where fifty-two men were arrested on May 11, 2001

HMS Cairo (D87), a ship in the Royal Navy

Cairo, Nebraska

Francesco Cairo, a 17th century Italian painter

Cairo Jim, a popular series of children's books by Australian author Geoffrey McSkimming

Cairo pentagonal tiling, a geometrical pattern

Cairo Foster, an Asian-American skateboarder

Cairo, a graphic novel by G. Willow Wilson and M.K. Perker

Cairo Road, an important thoroughfare in Lusaka, Zambia

Cairo (band), a progressive rock band

Cairo (typeface), a symbol typeface