C. S. Lewis, an Irish author and scholar of mixed Irish, English, and Welsh ancestry

Conselho Superior da Luta of Guinea-Bissau

Coordinated Science Lab, University of Illinois at Urbana-Champaign

Coupé Sport Lightweight, a high-performance version of the sports car BMW M3

Canadian Soccer League, the name of two separate soccer leagues; a former professional soccer league and the current re-branded name for the semi-professional Canadian Professional Soccer League

Canada Steamship Lines Inc., a Canadian shipping company

CSL Limited, an Australian supplier of blood products and vaccines

Comma-Separated List, a method of storing arrays in computer files; see Comma-separated values

Clay Sanskrit Library

Cosmopolitan Soccer League, a soccer league in the New York City area

Charter Seat License

Context-sensitive language, in mathematics, logic, and computer science, a formal language that can be defined by a context-sensitive grammar

CSL New World Mobility Group, a mobile phone company in Hong Kong

Crosshole Sonic Logging a nondestructive testing method used to determine the integrity of a constructed material.

CAL Spora Luxembourg, an athletics club in Luxembourg City, Luxembourg

Computerized Speech Lab

Citation style language

Central Science Laboratory, a laboratory services agency of the UK Department of Environment, Food and Rural Affairs

Computer Servo Lock, a technology Yamaha Electronics employs in its tuners and receivers

CSL is the ICAO airline designator for Minson Aviation trading as the California Air Shuttle, United States

Computer Systems Laboratory, at Stanford University, joint venture between Electrical Engineering and Computer Science in School of Engineering

Computer Science Laboratory, a laboratory of Xerox's research division, Xerox PARC; both the laboratory and the division are best known for essentially creating the modern personal computer graphical user interface (GUI) paradigm

Chinese Super League, the premier league of football (soccer) in the People's Republic of China