Cut and Paste Officer, a term used in jest to refer to officers who produce documents in the United Nations

Chief Post Office - main post office in a country/city/region.

Crude Palm Oil - a crude form of Palm Oil, an edible vegetable oil obtained from the fruit of the oil palm tree.

Calgary Philharmonic Orchestra

Chief Privacy Officer - an executive position in an organization responsible for data security

Compulsory Purchase Order

Chief Procurement Officer - an executive position in an organization focused on Supply Management (i.e. sourcing and procurement).

Capital Punishment Organization, a 1990s rap duo

Classic Produktion Osnabrück - a German producer of classical music CDs

Chief Process Officer - an executive position in an organization.

Certified Pre-Owned - a qualification for a used vehicle sold by dealers.

Certified Protection Officer - a certification indicating a level of skill and training for Security Officers, earned from the International Federation of Protection Officers

Chelsea Pitch Owners - an organisation which owns the naming rights of Chelsea Football Club and the Stamford Bridge freehold.

Chief Petty Officer - a military rank.

Close Protection Officer - a British police officer trained as a Bodyguard

Complete partial order, a term in mathematics

CPO is the ICAO airline designator for Corporate Aircraft Company, United States

Czech Philharmonic Orchestra (watch the redirect), based out of Prague.