Capsule launch system for space capsules

Cls. is an abbreviation of close, a type of road. The abbreviation is sometimes used on road signs.

Coffin-Lowry syndrome, a genetic disorder associated with mental retardation

Combat lifesaver (or combat medic) US Military Occupational Specialty 68W

Critical legal studies, a contentious school of legal philosophy, that emerged from Harvard Law School in the 1980s.

Columbia Law School at Columbia University

The Mercedes-Benz CLS-Class, a series of automobile models.

Critical language studies - the study of language that evolved into critical discourse analysis

Celestica Inc. (New York Stock Exhchange symbol: CLS).

Call logging system, a transaction logging system or interface.

Common Language Specification an open specification developed by Microsoft that describes the executable code and runtime environment. It defines an environment that allows multiple high-level languages to be used on different computer platforms without being rewritten for specific architectures.

Cory Lee Senn, rapper, leader of The M.O.B.

Covington Latin School, a high school in Covington, Kentucky

cls is a command in some operating systems, including MS-DOS, and programming languages, such as BASIC, that clears the screen.

Continuous linked settlement, a financial clearing system

Christian Legal Society

Nikon's Creative Lighting System, a complete lighting solution for Nikon's camera bodies and external light units.

Coalition of Latin@ Scholars at Teachers College, Columbia University

Chicago Linguistic Society

CLS Records, a record label.

City of London School (an all-boys school; see also City of London School for Girls.

Canadian Light Source - a synchrotron research facility located at the University of Saskatchewan, in Saskatoon, Saskatchewan

A polish Drum and Bass group signed to Med School, sister label of Hospital Records.