Cisco Connection Online, the name for the Cisco Systems' website

Chief Creative Officer - usually a title given to employees of advertising agencies and such

Chief Communications Officer - seniormost communications, public relations and/or public affairs officer in an organization

City Centre Offices, an English/German record label for electronic music

Chief Compliance Officer - in charge of regulatory compliance, especially Sarbanes-Oxley

Catholic Christian Outreach - A Catholic campus ministry organization in Canadian Universities

Coalition for Christian Outreach - A Christian campus ministry organization, based out of Pittsburgh, Pennsylvania

Conservative Central Office, the former name of the headquarters of the British Conservative Party

WCCO (AM), a commercial radio station broadcasting out of the Minneapolis-St. Paul, Minnesota metropolitan area. It is the clear channel broadcaster (not to be confused with Clear Channel Communications) in North America on the frequency of 830 kilohertz and one of the flagship stations of the CBS Radio broadcasting network.

Cataloguing Cultural Objects - A metadata standard developed by the Visual Resources Association

Cell Cycle Ontology - A formal ontology for describing the cell cycle process

Civilian Communications Officer, a staff position in London's Metropolitan Police Service