Brother's keeper is a Biblical phrase from William Tyndale's translation of the story of Cain and Abel. In Genesis 4:9, Cain questions his responsibility to look after his brother Abel: "Am I my brother's keeper?"

My Brother's Keeper: A Memoir and a Message, a book by Amitai Etzioni

"My Brother's Keeper", ER

My Brother's Keeper: A History of the American Jewish Joint Distribution Committee 1929-1939, a book by Yehuda Bauer

My Brother's Keeper (1995 film), a made-for-television film featuring Ellen Burstyn

My Brother's Keeper, a book by Bo Gritz

"Brother's Keeper" (Prison Break episode)

His Brother's Keeper, a novel by Peter Rawlinson, Baron Rawlinson of Ewell

Brother's Keeper (film), a 1992 documentary

"Brother's Keeper" (Miami Vice), pilot

My Brother's Keeper (TV series), a British sitcom starring George Layton

My Brother's Keeper, a comic book published by Spire Christian Comics

My Brother's Keeper (novel), by Marcia Davenport

My Brother's Keeper (2004 film), a film starring Christian Potenza

Brothers Keepers, a German-based transnational anti-racism project

My Brother's Keeper, a series of Star Trek books by Michael Jan Friedman

My Brother's Keeper, a book by Stanislaus Joyce, brother of James Joyce

Brother's Keeper (album), by Rich Mullins

"Brother's Keeper", Law & Order

My Brother's Keeper (2002 film), a made-for-television film starring Jeanne Tripplehorn

I Am Not My Brother's Keeper, an album by The Flaming Ember

My Brother's Keeper (Lake album)

Brother's Keeper, an album by The Neville Brothers

"Brother's Keeper", a song by Ying Yang Twins from U.S.A. (United State of Atlanta)

"Brother's Keeper", a song by Firewind from Burning Earth

"Am I My Brother's Keeper?", a song by Shyheim from Manchild

Brother's Keeper, an American punk rock band

Brother's Keeper (TV series), an American sitcom

His Brother's Keeper: A Story from the Edge of Medicine, a book by Jonathan Weiner

My Brother's Keeper (Charles Sheffield novel)

Brother's Keeper (software), a line of genealogy software