Vampire: The Masquerade - Bloodlines, a computer game based on the World of Darkness setting by White Wolf

Castlevania: Bloodlines, a Castlevania video game

One's bloodline is one's familial ancestry. Bloodline or Bloodlines may also refer to:

Bloodlines (Blade: The Series episode), an episode of the action-horror series Blade: The Series

Bloodline (album), a 1992 album by Recoil

Hellraiser: Bloodline, the fourth entry in the Hellraiser horror film series

Bloodlines (VTES), an expansion set for the Vampire: The Eternal Struggle collectible card game based on the World of Darkness setting by White Wolf

Bloodline (film), a 1979 film

Bloodline (World of Darkness), vampire groups in the Vampire: The Masquerade and Vampire: The Requiem role-playing games by White Wolf

Bloodline Records, a record label founded by rapper DMX

Bloodlines (TNG episode), a 7th season episode of the science fiction series Star Trek: The Next Generation

Star Wars Republic 64: Bloodlines, the sixty-fourth issue of the Star Wars: Republic comic book series

Blood Lines, a short story collection by British crime-writer Ruth Rendell

Bloodlines (TV drama), a one-off detective thriller starring a released suspect played by Kevin McNally

Bloodline, a first-person shooter by Czech game developer Zima Software.

Bloodline (novel), a 1977 novel by Sidney Sheldon

Bloodlines (comics), a DC Comics crossover

Bloodlines (novel), a Star Wars novel

Bloodlines, a collection of Hellblazer stories written by Garth Ennis

Smokin' the Dummy/Bloodlines, a 1983 album by Terry Allen.

Bloodline, a 2001 Slayer song on the album God Hates Us All

Bloodlines (CSI episode), an episode of the crime series CSI: Crime Scene Investigation