The Andromeda Strain (1968), a novel by Michael Crichton

Andromeda Galaxy, named after the constellation in which it is located

A for Andromeda, a 1961 BBC TV series remade in 2006

Andromeda, the superweapon used in the video game Megaman Star Force, capable of destroying entire star systems

Andromeda Shun, one of five main characters in the popular manga/anime Saint Seiya

The Andromeda Strain (film) (1971), a film based on the novel

Andromeda (DC Comics), the codename of Laurel Gand of the Legion of Super-Heroes

Andromeda (constellation), depicting the mythological character

Andromeda (Marvel Comics), a native of Atlantis and member of the Defenders

Andromeda (novel) a.k.a. Andromeda Nebula, a science fiction novel by Ivan Yefremov

Two Guys from Andromeda, game designers and creators of the Space Quest computer games

Andromeda (mythology), in Greek mythology, the daughter of Cepheus and Cassiopeia, wife of Perseus

Andromeda, the common name for several species of plant in genus Pieris

Andromeda class attack cargo ship, used in World War II

Andromeda (band), a progressive metal band from Sweden

Andromeda polifolia, the monotypic genus containing bog-rosemary, a plant of the heath family

Andromedans (extraterrestrial), the name given to what are said to be a group of extraterrestrials from the Andromeda Galaxy

Alesis Andromeda, a brand of synthesizer

Andromeda (British band), a 1960's psychedelic hard rock band featuring John Du Cann

Mount Andromeda, in Canada and the Antarctic

Andromeda (TV series), a science fiction television series about the Andromeda Ascendant, the fictional starship featured in that series

In the second season of the anime series Star Blazers (Space Battleship Yamato), the Andromeda is the flagship of the Earth Defence Fleet.

Andromeda, a flying model rocket previously produced by Estes Industries during the 1970s and 1980s.