Paul Ehrlich's pioneering experiments with cells and body tissue revealed the fundamental principles of the immune system and established the legitimacy of chemotherapy--the use of chemical drugs to treat disease. His discovery of a drug which cured syphilis saved many lives and demonstrated the potential of systematic drug research. His studies of dye reactions in blood cells helped establish hematology--the scientific field concerned with blood and blood-forming organs--as a recognized discipline. Many of the new terms he coined as a way to describe his innovative research, including "chemotherapy," are still in use. From 1877 to 1914, Ehrlich published 232 papers and books, won numerous awards, and received 5 honorary degrees. In 1908, Ehrlich received the Nobel Prize in medicine or physiology. Along with Robert Koch, Nobel Prize winner in 1905, and Emil Behring, Nobel Prize winner in 1901, he is considered one of the "Big Three" in medicine. Ehrlich, Koch, and von Behring were contemporaries...