Nancy Wexler's research on Huntington's disease has led to the development of a presymptomatic test for the condition, as well as the identification of the genes responsible for the disease. The symptoms of this fatal, genetically based disorder (for which Wexler herself is at risk) usually appear around middle age, and the disease leads to the degeneration of mental, psychological, and physical functioning. For her pivotal role in these achievements, Wexler was granted the Albert Lasker Public Service Award in 1993.

Nancy Sabin Wexler was born to Milton Wexler, a Los Angeles psychoanalyst, and Leonore Sabin Wexler. She studied social relations and English at Radcliffe and graduated in 1967. Wexler subsequently traveled to Jamaica on a Fulbright scholarship and studied at the Hampstead Clinic Child Psychoanalytic Training Center in London.

In 1968, Wexler learned that her mother had developed the symptoms of Huntington's disease, a condition to which Wexler's maternal grandfather...