A vehement anti- smoker, he took every opportunity to warn against the dangers of tobacco, even in his acceptance speech for the Nobel Prize.
Howard Martin Temin was born in Philadelphia on December 10, 1934, to Henry Temin, a lawyer, and Annette (Lehman) Temin. The second of three sons, Temin showed an early aptitude for science and first set foot in a laboratory when he was only fourteen years old. As a student at Central High School in Philadelphia, he was drawn to biological research and attended special student summer sessions at the Jackson Laboratory in Bar Harbor, Maine. After graduation from high school, Temin enrolled at Swathmore College in Pennsylvania, where he majored and minored in biology in the school's honors program. He published his first scientific paper at the age of eighteen, and was described in his college yearbook as "one of the future giants in experimental biology."
After graduating from Swathmore in 1955, Temin spent the summer at the Jackson Laboratory and enrolled for the fall term at the California Institute of Technology in Pasadena. For the first year and a half, he majored in experimental embryology but then changed his major to animal virology. He studied under Renato Dulbecco, a renowned biologist, who worked on perfecting techniques for studying virus growth in tissue and developed the first plaque assay (a chemical test to determine the composition of a substance) for an animal virus.
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