The yeast artificial chromosome, which is often shortened to YAC, is an artificially constructed system that can undergo replication. The design of a YAC allows extremely large segments of genetic material to be inserted. Subsequent rounds of...

Yeast artificial chromosomes (YAC) are cloning vectors. Regular cloning vectors have size limits for their DNA inserts. Plasmids can take up to 10 kilobases of DNA. Bacteriophages take 15 kilobases of DNA. Cosmids can take up to 50 kilobases of DNA....

A yeast artificial chromosome (short YAC) is a vector used to clone large DNA fragments (larger than 100 kb and up to 3000 kb). It is an artificially constructed chromosome and contains the telomeric, centromeric, and replication origin sequences needed...

Eleven years ago, scientists shocked the public when they produced larger-than-life mice by inserting a rat gene for growth hormone. Transgenic animals, then considered a miracle of genetic engineering, quickly took their place as laboratory workhorses essential in many types of research and...

Huntington F. Willard and his colleagues have synthesized the first artificial human chromosome. The chromosome survived in cells for as long as 6 months and replicated. The discovery may aid understanding of how a gene's chromosomal context influence its genetic activity. For chefs,...