Tumor suppressor genes regulate mitosis and cell division. When their function is impaired, the result is a high rate of uncontrolled cell growth or cancer. Damage to tumor suppressor genes contributes to a large number of different types of tumors....

Cell proliferation is a highly regulated process in which two classes of genes play crucial roles, proto-oncogenes and tumor suppressor genes. Proto-oncogenes induce cell proliferation, and tumor suppressor genes control the levels of proto-oncogenic...

A tumor suppressor gene is a gene that reduces the probability that a cell in a multicellular organism will turn into a tumor cell. A mutation or deletion of such a gene will increase the probability of the formation of a...

Biologist Marguerite Vogt succeeded by focusing singularly on her goal -- advancing science.She studied how organisms develop, then applied insights to make important strides in polio and cancer research.Several newer drugs and targeted therapies wouldn't exist now, scientists say, had Vogt and a fellow researcher's...