Beginning at the moment of conception, the human organism depends upon adequate nutrition for growth, development, and survival. In the first week from the fertilization, the zygote produces a series of blastomeres and, because of further cellular...

Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ. The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes...

SUMMARY The expression of transforming growth factor-beta2 (TGF-beta2) appears to play a strong role in the establishment and progression of glial tumors. In particular, elevated expression of TGF-beta2 appears to be responsible for the impaired cellmediated immunity often observed in patients with a...

SUMMARY Using five trophoblast cell lines of different differentiation status, we have shown that trophoblasts could constitutively release the transforming growth factor beta-I (TGBeta1), but not TGFbeta2. Treatment of the human tumorigenic, TL, and BeWo cells with a differentiating agent and a potent...

A group of researchers has discovered a mechanism that helps protect deer mice from hantavirus even though the rodents carry the life-threatening disease.The research could pave the way for new therapies for treating hantavirus and other so-called zoonotic diseases transmitted to humans by animals _...