A protein which enters the NUCLEUS of a CELL and binds to a region of DNA, initiating or regulating the TRANSCRIPTION of a GENE into MRNA (messenger RNA). FIONA...

Transcription factors are protein complexes that help RNA polymerase bind to DNA. RNA polymerase is the enzyme that transcribes genes to make messenger RNA, which is then used to make protein. By controlling RNA polymerase's access to the gene,...

In the field of molecular biology, a transcription factor (sometimes called a sequence-specific DNA binding factor) is a protein that binds to specific parts of DNA using DNA binding domains and is part of the system that controls the transfer (or...

Panomics' array-based kits map transcription factor networks A single human cell contains around 2,000 transcription factors, estimates Jason Li, president and CEO of Panomics in Redwood City, Calif. Their shifting alliances comprise a powerful layer of gene expression regulation, and can change depending...

The importance of transcriptional regulation, coupled with the fact that transcription factors are influenced by a variety of stimuli and can be modulated through several different biochemical modifications, suggest that intervention at the point of transcription is a promising strategy for the development...