Telomeres are structures found at the ends of chromosomes in the cells of eukaryotes. Telomeres function by protecting chromosome ends from recombination, fusion to other chromosomes, or degradation by nucleases. They permit cells to distinguish...

Telomeres are specialized DNA regions that consist of short, tandemly repeated sequences at the ends of linear chromosomes. Telomeres are found in all eukaryotes and are essential for normal cell growth. During DNA replication, telomeres complete the...

A protective structure at the ends of CHROMOSOMES; see...

A telomere is a region of highly repetitive DNA at the end of a linear chromosome that functions as a disposable buffer. Every time linear chromosomes are replicated during late S phase, the DNA polymerase complex is incapable of replicating all the way...

Analysis of telomeres, the nucleoprotein complexes that physically cap and protect the ends of eukaryotic chromosomes, has a long and intriguing history. The recent resurgence of plant telomere biology prompted us to recap this history to provide background and context for current investigations addressing...

ABSTRACT: The highly conserved multiple repeats of short oligonucleotide sequences that cap the ends of eukaryotic chromosomes have become of increasing interest and speculation as their relationship with cell cycling and cell life-spans has been revealed. Most new information has come from the study...

Essay describes aging as a result of telomeric shortening and damage.