In substitution reactions, one atom or radical replaces another. The most common type of substitution reactions of compounds of metals is ion exchange accompanied by precipitation. The most common substitution reactions of compounds of non-metallic...

In a substitution reaction, a functional group in a particular chemical compound is replaced by another group. In organic chemistry, the electrophilic and nucleophilic substitution reactions are of prime importance. Organic substitution reactions are...

Aromatic substitution underwent a renaissance in the 1980s and today offers a range of new methods which give access to complex or unusual compounds From the earliest years of aromatic chemistry, when men such as Kekule, Dewar and Baeyer were jockeying for...

Reactions of various zirconacyclopentadienes bearing alkyl and aryl groups with 6-alkynylpurines in the presence of NiBr^sub 2^(PPh^sub 3^)^sub 2^ afforded the corresponding 6-arylpurines with highly hydrophobic aryl moieties in low to moderate yields. Some of the title purines showed interesting cytostatic activity. Keywords:...