E.B. White's novel tells the story of Stuart Little, a small and gentlemanly mouse, as he grows up in New York City and pursues his love of adventure. Although he has many adventures, Stuart's greatest one is meeting a beautiful bird named Margalo, with whom he immediately falls in love. When Margalo mysteriously disappears, Stuart resolves to find her. He ventures into the world on his own, determined to see his friend once again. On his journey, Stuart learns a great many things, illustrating White's themes of the effects of appearance, an adventurous spirit and courage, true friendship, gentlemanly propriety, and journeying forward.