Pellagra, a niacin deficiency disease, begins unremarkably, usually with weakness, skin rash, mouth sores, and loss of appetite. Unless checked, however, it gradually worsens, producing severe inflammation of the skin, mental disturbances, and...

1874-1929 American physician and epidemiologist who is best known for demonstrating that pellagra is a nutritional deficiency disease. Pellagra is characterized by dermatitis, diarrhea, and dementia. The disease was endemic in areas where the diet was...

Pellagra is a vitamin deficiency disease caused by dietary lack of niacin (vitamin B3) and protein, especially proteins containing the essential amino acid tryptophan.[1] Because tryptophan can be converted into niacin, foods with tryptophan but without...

Case Report Pellagra is a nutritional disease with cutaneous, gastrointestinal, and neuropsychiatric manifestations. Because of the diversity of pellagra's signs and symptoms, diagnosis is difficult without an appropriate index of suspicion. Untreated, pellagra is fatal. Two cases of pellagra in contemporary homeless people...

Abstract Pellagra is a nutritional wasting disease attributable to a combined deficiency of tryptophan and niacin (nicotinic acid). It is characterized clinically by four classic symptoms often referred to as the four Ds: diarrhea, dermatitis, dementia, and death. Prior to the development...