Pellagra, a niacin deficiency disease, begins unremarkably, usually with weakness, skin rash, mouth sores, and loss of appetite. Unless checked, however, it gradually worsens, producing severe inflammation of the skin, mental disturbances, and...

1874-1929 American physician and epidemiologist who is best known for demonstrating that pellagra is a nutritional deficiency disease. Pellagra is characterized by dermatitis, diarrhea, and dementia. The disease was endemic in areas where the diet was...

Pellagra is a vitamin deficiency disease caused by dietary lack of niacin (vitamin B3) and protein, especially proteins containing the essential amino acid tryptophan.[1] Because tryptophan can be converted into niacin, foods with tryptophan but without...