Although there are characteristics whose inheritance adheres strictly to Mendel's predictions, more often than not, that is not the case. Many different mechanisms can alter the phenotypic expression of an inherited genotype, complicating attempts to...

Maternal inheritance is a type of uniparental inheritance in which all the progeny of a mating inherit the genotype and phenotype of the female parent. It is an extreme form of non-Mendelian inheritance and is seen as the failure of the progeny to...

Gregor Mendel was fortunate to have chosen some of the most genetically simple of characters in the garden pea for his seminal experiments that laid the foundation for the science of genetics. Each was determined by a single gene on a different...

Inheritance patterns are the predictable patterns seen in the transmission of genes from one generation to the next, and their expression in the organism that possesses them. (A gene is said to be expressed when it is read by cellular mechanisms that...

ABSTRACT A genetic investigation of strain d4-95, which carries a recessive mutant allele (pwB^sup 95^) of pawn-B, one of the controlling elements of voltage-dependent calcium channels in Paramecium tetraurelia, revealed a non-Mendelian feature. Progeny of the cross between d4-95 and wild type often...

ABSTRACT Telomeres are an unusual component of the genome because they do not encode genes, but their structure and cellular maintenance machinery (which we define as "telotype") are essential for chromosome stability. Cells can switch between different phenotypic states. One such example is...