A missense mutation is a change in the nucleic acid base sequence (e.g., the polynucleotide sequence found in DNA) that results in a change in the order of amino acids in the protein chain resulting from the translation of that sequence. As with all...

In genetics, missense mutations or nonsynonymous mutations are types of point mutations where a single nucleotide is changed to cause substitution of a different amino acid. This in turn can render the resulting protein nonfunctional. Such mutations are...