Locus control regions are defined as gene regulatory sequences that are able to direct high-level and tissue-specific expression of a transgene, independent of its site of integration the host genome. These regions influence the mechanisms of gene...

Post-translational control can be defined as the mechanisms by which protein structure can be altered after translation. Proteins are polymers of amino acids, and there are twenty different amino acids. Both the order and identity of these amino acids...

Housekeeping genes are responsible for cell maintenance and activity, and their products are therefore essential for general cell physiology. Housekeeping genes are so denominated because they encode proteins required for common and essential...

Genes, the biological units of inheritance, are present in all living organisms. The majority of the time these genes are silent; they are not expressed. At certain times, however, genes are switched on to produce their particular product. This...

Gene expression is the process by which the inheritable information in a gene, such as the DNA sequence, is made into a functional gene product, such as protein or RNA. Several steps in the gene expression process may be modulated, including the...

A new path Findings may provide clues to age-related diseases Ann Arbor, MI-Results from gene microarray studies by researchers at the University of Michigan reveal there are highly specific, age-- related changes in retinal gene expression. Those findings are described in...

Noordwijk, Netherlands - Gene expression profiling is considered by most experts in the field to be one of the frontlines in combating melanoma, with recent breakthroughs having the potential to transform current approaches to melanoma diagnosis and prognosis. University of California, San Francisco...