Functional Group
A molecule's functional group is the chemically reactive portion, or segment, of an organic chemical molecule. In this sense, the functional group determines most of a compound's chem...
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Organic Functional Group
Organic functional groups are the section of the organic molecule which controls the reactivity of the molecule. For example the presence of multiple bonds between carbon atom...
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The United States Pharmacopia has been recognized for years as an authoritative compendium on drug standards. In recent years, it has paid increasing attention to "microbial purity," i.e., freedom ...
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This month's instalment of "LC Troubleshooting" presents two examples of sample degradation inside the liquid chromatography (LC) column. Depending upon the type of samples you analyse, sample degr...
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When publishing a dossier, life science companies typically struggle with efficiently compiling supporting documentation. Usually this is the result of dealing with multiple formats and sources, in...
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Since the introduction of dialysis 30 years ago, membranes have proven to be useful tools for the separation of polar and ionic compounds in a variety of applications, including drugs from biofluid...
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ABSTRACT
Improved feedstream titers are driving a demand for increased downstream processing productivity as manufacturers seek to lower the costs of monoclonal antibodies ...
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Near-infrared spectroscopy (NIRS) is an analytical technique based on absorption measured in the near-infrared region of the electromagnetic spectrum that is between the visible and the mid-infrare...
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Antibody-based therapeutics are expected to continue to be a major source of new therapies for the next decade. However, monoclonal antibodies (MAbs) are among the world's most expensive drugs. Pre...
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Even at minute quantities, unwanted chemicals present in pharmaceutical ingredients may greatly influence a drug product's efficacy and safety. While researchers strive to eliminate or control impu...
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BIOLOGICS
BIO Raises Concerns About Studies on Follow-On Biologics
Washington, DC (Feb. 22)—The Biotechnology Industry Organization (BIO, Washington, DC, www.bio.org|~
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Mefenamic acid (MA) [N–(2, 3–xylyl) anthranilic acid] is a high-dose, non-steroidal anti-inflammatory agent available in immediate-release capsule and tablet formulation. It is poorly s...
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Functional Group
USP Chapter Emphasizes Problems With Revision Process
