A frame shift is a shift in the sequence that DNA (deoxyribonucleic acid) is read. DNA is transcribed into messenger ribonucleic acid, the blueprint for the manufacture of protein, by being read in frames of three bases at a time by the transcription...

A frameshift mutation (also called a frameshift or a framing error) is a genetic mutation caused by indels, ie. inserts or deletes a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene...

Gu LH, Kim SC, Ichiki Y, Park J, Nagai M, Kitajima Y. J Invest Dermatol 2003 Sep: 121(3):482-5. The authors report a unique familial type of epidermolysis bullosa simplex (EBS) and a novel mutation in the keratin gene KRT5, i.e., a frameshift...

ABSTRACT UV irradiation, a known carcinogen, induces the formation of dipyrimidine dimers with the predominant lesions being cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone adducts (6-4PPs). The relative roles of the yeast translesion synthesis DNA polymerases Polζ and Polη in UV survival...