During mitosis in a typical plant or animal cell, each chromosome divides longitudinally into two sister chromosomes that eventually separate and travel to opposite poles of the mitotic spindle. At the beginning of mitosis, when the sister chromosomes...

The centromere is the region of the CHROMOSOMES in which the two chromatids are...

The centromere is a region in the middle of the chromosome involved in cell division and the control of gene...

RESEARCH ARTICLE The centromere of eukaryotic chromosomes is essential for the faithful segregation and inheritance of genetic information. In the majority of eukaryotic species, centromeres are associated with highly repetitive DNA, and as a consequence, the boundary for a functional centromere is difficult...

INSIGHT Centromeres evolve rapidly and display a remarkable lack of sequence conservation (Henikoff et al., 2001). They can be small (125 bp in Saccharomyces cerevisiae) or large (9 million bp in maize) and show a relatively ordered arrangement of long repeats (Schizosaccharomyces pombe)...